MYB Pre-design Chimera RNAi
产品名称： MYB Pre-design Chimera RNAi
英文名称： MYB Pre-design Chimera RNAi
产品编号： H00004602-R01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Homo sapiens v-myb myeloblastosis viral oncogene homolog (avian) (MYB), mRNA.
- Reactivity:
- Human
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_005375
- Note:
- Position of the Chimera RNAi.
-
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 4602
- Gene Name:
- MYB
- Gene Alias:
- Cmyb,c-myb,c-myb_CDS,efg
- Gene Description:
- v-myb myeloblastosis viral oncogene homolog (avian)
- Omim ID:
- 189990
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq
- Other Designations:
- Avian myeloblastosis viral (v-myb) oncogene homolog,OTTHUMP00000017258,c-myb protein (140 AA),c-myb10A_CDS,c-myb13A_CDS,c-myb14A_CDS,c-myb8B_CDS,v-myb avian myeloblastosis viral oncogene homolog,v-myb myeloblastosis viral oncogene homolog
- Related Disease
- alpha-Thalassemia
- Anemia, Sickle Cell
- Anemia, sickle cell
- Asthma
- Asthma
- Atherosclerosis
- beta-Thalassemia
- Cardiovascular Diseases
- Coronary Artery Disease
- Diabetes Mellitus, Type 2
- Edema
- Genetic Predisposition to Disease
- Graft Occlusion, Vascular
- Hypertension
- Myocardial Infarction
- Nasal Polyps
- Obesity
- Pain
- Thalassemia