产品概述：Purified recombinant protein of Mouse integral membrane protein 2C (Itm2c), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

蛋白长度：A DNA sequence from Mouse cDNA ORF Clone, [GM33272V], encoding Mouse full-length Itm2c.

表达系统：HEK293T

种属：Mouse

标签类型：C-MYC/DDK

分子量：30.5 kDa

通用名：Itm2c

总结：Negative regulator of amyloid-beta peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation.[UniProtKB/Swiss-Prot Function]

形式：Liquid

浓度：>50 ug/mL as determined by microplate BCA method

纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining

储存溶液：25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

别名：3110038L02Rik; BRI3; Bricd2c; E25; E25C; ITM3