Product Information
    
 
    

    

        

            

                

                
Product Name
                
                

                
Cat#
                
                

                
Size
                
                

                
Price（¥）
                
            
            

                

                
 
                
Recombinant Human Interleukin-1 beta (Human IL-1β)
                
 
                
                

                
90101ES10
                
                

                
10 μg
                
                

                
1855.00
                
            
            

                

                
90101ES60
                
                

                
100 μg
                
                

                
10215.00
                
            
            

                

                
90101ES76
                
                

                
500 μg
                
                

                
26545.00
                
            
        
    
    
    
 
    
Product Description
    
 
    
Interleukin-1 beta (IL-1β) is a pro inflammatory cytokine, which is secreted by immune cells to trigger inflammation and this has been found profoundly in the lesions caused by Leishmania pathogens. IL-1 is a name that designates two pleiotropic cytokines, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2), which are the products of distinct genes. IL-1 alpha and IL-1 beta are structurally related polypeptides that share approximately 21% amino acid (aa) identity in human. Both IL-1α and IL-1β binds to the same receptor and has similar but not identical biological properties; The mature human IL1β shares 96% amino acid sequence identity with rhesus and 67%-78%  with canine, mouse and rat IL-1β.IL-1β, are known to modulate effects of neurotoxic neurotransmitters discharged during excitation or inflammation in the central nervous system (CNS).
    
 
    
Product Properties
    
 
    

    

        

            

                

                
Synonyms
                
                

                
Interleukin-1 beta, IL-1β, IL-1, IL1B, IL-1b, IL1-BETA, IL-1F2, IL1F2IL-1 beta, interleukin-1 beta, preinterleukin 1 beta, pro-interleukin-1-beta.
                
            
            

                

                
Accession
                
                

                
P01584
                
            
            

                

                
GeneID
                
                

                
3553
                
            
            

                

                
Source
                
                

                
E.coli-derived human IL-1β protein, Ala117-Ser269.
                
            
            

                

                
Molecular Weight
                
                

                
Approximately 17.3 kDa.
                
            
            

                

                
AA Sequence
                
                

                
APVRSLNCTL RDSQQKSLVM SGPYELKALH LQGQDMEQQV VFSMSFVQGE ESNDKIPVAL GLKEKNLYLS CVLKDDKPTL QLESVDPKNY PKKKMEKRFV FNKIEINNKL EFESAQFPNW YISTSQAENM PVFLGGTKGG QDITDFTMQF VSS
                
            
            

                

                
Tag
                
                
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